| Gene Symbol | RNF8 |
| Aliases | Page for RNF8 |
| Chromosome | 6p21.1 |
| Protein Type | Ligase |
| Function | Recognition: Following DSB formation, ATM kinase phosphorylates histone H2AX (generating γ-H2AX), which serves as a platform for recruiting additional repair proteins [1]. |
| UniProt ID | Q9UPW4 |
| NCBI Gene ID | 9027 |
| Ensembl ID | ENSG00000137243 |
| OMIM | 611685 |
| GeneCards | RNF8 |
| Human Protein Atlas | RNF8 |
| Gene Name | Ring Finger Protein 8 |
| Categories | DNA Repair, Genome Stability, Ubiquitin-Proteasome System |
| Associated Diseases | neurodegeneration |
| Interactions | ATM, MDC1, BRCA1, CANCER |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsHPASTRING |