| Gene Symbol | RPA3 |
| Full Name | Replication Protein A3 |
| Chromosome | 7q32.3 |
| Function | is a subunit of the heterotrimeric Replication Protein A complex (RPA), the major single-stranded DNA (ssDNA)-binding protein in eukaryotic cells. |
| Molecular Weight | 70 kDa |
| UniProt ID | [P35274](https://www.uniprot.org/uniprot/P35274) |
| Ensembl ID | ENSG00000186871 |
| GeneCards | RPA3 |
| Human Protein Atlas | RPA3 |
| RPA1 (RPA70) | 70 kDa subunit - contains multiple DNA-binding domains (DBDs) and protein interaction domains |
| RPA2 (RPA32) | 32 kDa subunit - phosphorylated in response to DNA damage, regulates protein interactions |
| RPA3 (RPA14) | 14 kDa subunit - smallest subunit, essential for complex assembly and stability |
| Associated Diseases | Cancer, Glioblastoma, Ms, Tumor |
| KG Connections | 8 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |