| Gene Symbol | SLC12A5 |
| Full Name | Solute Carrier Family 12 Member 5 (K⁺/Cl⁻ Cotransporter 2, KCC2) |
| Aliases | Potassium Chloride Cotransporter 2, KCC2 |
| Chromosome | 20q13.12 |
| Protein Type | Transporter |
| Function | is a critical determinant of the polarity of GABAergic signaling, as it establishes the low intracellular chloride concentration required for hyperpolarizing GABA-A receptor responses. |
| Pathways | autophagy pathway |
| UniProt ID | Q9NPJ9 |
| NCBI Gene ID | 57468 |
| Ensembl ID | ENSG00000124140 |
| OMIM | 607707 |
| GeneCards | SLC12A5 |
| Human Protein Atlas | SLC12A5 |
| Developmental Stage | Primary Transporter |
| Embryonic/Early Postnatal | NKCC1 |
| Associated Diseases | ALS, depression |
| Interactions | GENES |
| KG Connections | 97 knowledge graph edges |
| Databases | GeneCardsHPASTRING |