gene 640 words KG: SYN2 2026-03-21
kind:genesection:genesstate:published
Contents

SYN2 Gene

🧬 Gene Info
Gene SymbolSYN2
Full NameSynapsin II
Chromosome3p25.2
Protein FamilySynapsin family
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionpresynaptic terminals of neurons throughout the brain[@masliah2000]
Amino Acids706 aa
PathwaysMAPK, MAPK pathway
UniProt ID[Q9UQ88](https://www.uniprot.org/uniprot/Q9UQ88)
Ensembl IDENSG00000153147
OMIM185600
GeneCardsSYN2
Human Protein AtlasSYN2
Chromosomal location3p25.2
Gene familySynapsin family
Associated DiseasesALS, Autism, Epilepsy, Schizophrenia, autism spectrum disorder
KG Connections104 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Pyroptosis in Neurodegeneration
mechanism · KG edge: therapeutic_target
Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: expressed_in
Packard Center for ALS Research
institution · KG edge: associated_with
Dementia Australia
institution · KG edge: therapeutic_target
Alzheimer Indonesia
institution · KG edge: expressed_in

Knowledge Graph (12 edges)

SYN2 involved_in synaptic vesicle cycling
SYN2 involved_in axon outgrowth
SYN2 implicated_in autism spectrum disorders
SYN2 biomarker_for GAD1
SYN2 biomarker_for SYP
SYN2 biomarker_for SLC32A1
SYN2 biomarker_for GRIN2A
SYN2 biomarker_for PVALB
SYN2 biomarker_for SNAP25
SYN2 contributes_to SYN1