gene 1,474 words KG: TK2 2026-03-28
kind:genesection:genesstate:published
Contents

TK2 Gene

🧬 Gene Info
Gene SymbolTK2
Full NameTK2
Protein TypeProtein
FunctionThymidine kinase 2 (TK2) is a mitochondrial enzyme that catalyzes the phosphorylation of thymidine, deoxyuridine, and deoxycytidine.
Molecular Weight62 kDa
Amino Acids265 aa
UniProt IDSearch UniProt
NCBI Gene IDSearch NCBI
GeneCardsTK2
Human Protein AtlasTK2
Associated Diseasesneurodegeneration
KG Connections30 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
Digital Twin-Guided Metabolic Reprogramming
Score: 0.61
Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: expressed_in
TYMP Gene
gene · KG edge: associated_with
TWNK Gene
gene · KG edge: associated_with
TFAM Gene
gene · KG edge: associated_with
SUCLG1 — Succinate-CoA Ligase GDP Forming Subunit Alpha
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TK2 associated_with SUCLA2
TK2 associated_with SUCLG1
TK2 associated_with TFAM
TK2 associated_with POLG
TK2 associated_with RNASEH1
TK2 associated_with OPA1
TK2 associated_with TWNK
TK2 associated_with MPV17
TK2 associated_with DGUOK
TK2 associated_with TYMP