| Gene Symbol | MFN2 |
| Aliases | Mitofusin 2 |
| Chromosome | 1p36.22 |
| Function | Trans-tethering: HR2 domains form antiparallel complexes between adjacent mitochondria |
| Molecular Weight | 84 kDa |
| Amino Acids | 757 aa |
| Exons | 17 |
| Pathways | NF-κB, AMPK |
| GeneCards | MFN2 |
| Human Protein Atlas | MFN2 |
| Feature | MFN2 |
| Tissue expression | Broad, high in muscle |
| GTPase activity | Higher |
| ER contacts | Yes |
| Mitophagy role | Major |
| Associated Diseases | Als, CHARCOT-MARIE-TOOTH, Charcot-Marie-Tooth Type 2A, Fibrosis, Hereditary Polyneuropathy, Huntington |
| Known Drugs/Compounds | 8015-P2, Piperine |
| Interactions | GSDMD, RIPK1, RAB7A, CAT, CCR5, APP |
| KG Connections | 729 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |