protein 602 words KG: TYMP 2026-03-14
kind:proteinsection:proteinsstate:published
Contents

Thymidine Phosphorylase Protein

🔬 Protein Info
Gene SymbolTYMP
Full NameThymidine Phosphorylase
Chromosome22q13.33.
Protein TypeProtein
FunctionThymidine phosphorylase (TYMP) catalyzes the reversible phosphorolysis of thymidine to thymine and 2-deoxyribose-1-phosphate.
Amino Acids482 aa
UniProt IDSearch UniProt
GeneCardsTYMP
Human Protein AtlasTYMP
Associated DiseasesNeuropathy
InteractionsVEGFA, IL1B
KG Connections47 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.47
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (7)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (12)

Animal Model Comparison for Neurodegenerative Disease Therap
clinical · proposed · Score: 0.40
Endocannabinoid System Dysfunction Validation in Parkinson's
clinical · proposed · Score: 0.40
Glymphatic-Circadian Axis Enhancement Therapy for Parkinson'
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
Neural Oscillation Dysfunction Validation in Parkinson's Dis
clinical · proposed · Score: 0.40

See Also (12)

Packard Center for ALS Research
institution · KG edge: expressed_in
TK2 Gene
gene · KG edge: associated_with
SUCLG1 — Succinate-CoA Ligase GDP Forming Subunit Alpha
gene · KG edge: associated_with
SLC25A4 Gene
gene · KG edge: associated_with
POLG2 Gene — DNA Polymerase Gamma 2, Accessory Subunit
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TYMP biomarker_for TNF
TYMP biomarker_for DISC1
TYMP biomarker_for PRDM1
TYMP associated_with RRM2B
TYMP associated_with TK2
TYMP associated_with SUCLA2
TYMP associated_with SUCLG1
TYMP associated_with TFAM
TYMP associated_with POLG
TYMP associated_with RNASEH1