gene 1,634 words KG: TUBB1 2026-03-29
section:geneskind:genetopic:alzheimerstopic:parkinsons
Contents

TUBB1 — Tubulin Beta 1

🧬 Gene Info
Gene SymbolTUBB1
Full NameTubulin Beta 1
Chromosome9q34.3
Functionis a gene located on chromosome 9q34.
Primary Expressionmegakaryocytes and platelets, it is also expressed in neurons where it contributes to microtubule assembly, axonal transport, and cytoskeletal stabili
Molecular Weight50 kDa
Amino Acids445 aa
Exons4
Pathwaysoxidative stress response
GeneCardsTUBB1
Human Protein AtlasTUBB1
IsotypePrimary Expression
TUBB (class I)Ubiquitous
TUBB2A/BCNS neurons
TUBB3CNS neurons
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsCANCER, RNA, AND
KG Connections28 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.48
Quantum Coherence Disruption in Cellular Communication
Score: 0.34

Related Analyses (3)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

Related Experiments (5)

Anti-Tau Therapy Failure Mechanism in PSP — Why Clinical Tri
clinical · proposed · Score: 0.40
Brainstem Circuit Modulation for PSP
clinical · proposed · Score: 0.40
Levodopa Response Determinants in PSP — Biomarker-Guided Pre
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40
PSP and CBS Biomarker Validation Study
clinical · proposed · Score: 0.40

See Also (7)

MMP3 Gene
gene · KG edge: therapeutic_target
ICAM1 - Intercellular Adhesion Molecule 1
gene · KG edge: therapeutic_target
HMGCR — 3-Hydroxy-3-Methylglutaryl-CoA Reductase
gene · KG edge: expressed_in
cxcl8
gene · KG edge: therapeutic_target
CCL20 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

TUBB1 expressed_in HMGCR
TUBB1 activates cancer
TUBB1 therapeutic_target MMP3
TUBB1 therapeutic_target CXCL8
TUBB1 therapeutic_target Rb
TUBB1 inhibits Cancer
TUBB1 inhibits CANCER
TUBB1 expressed_in Cardiovascular
TUBB1 activates Prostate Cancer
TUBB1 therapeutic_target RNA