| Gene Symbol | UBR4 |
| Full Name | Ubiquitin Protein Ligase E3 Component N-Recognin 4 |
| Chromosome | 1p36.21 |
| Protein Type | Ligase |
| Function | encodes a large E3 ubiquitin ligase that plays critical roles in the N-end rule pathway and general protein quality control. |
| Primary Expression | Brain, Retina, Peripheral tissues |
| Molecular Weight | 500 kDa |
| UniProt ID | Q6ZNA4 |
| NCBI Gene ID | 54716 |
| GeneCards | UBR4 |
| Human Protein Atlas | UBR4 |
| Stress response | Turnover of damaged proteins |
| Signal transduction | Degradation of signaling components |
| Development | Temporal protein regulation |
| Associated Diseases | neurodegeneration |
| Interactions | AGING, UBIQUITIN |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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