| Gene Symbol | ATP7B |
| Aliases | ATP7BPROTEIN |
| Chromosome | 13q14.3. |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | hepatocytes, where it [@czonkowska2018] supports both copper incorporation into ceruloplasmin and biliary copper excretion |
| Subcellular Localization | </strong></td><td>Trans-Golgi network, cytoplasmic vesicles, canalicular membrane</td></tr> |
| Molecular Weight | 165 kDa |
| Amino Acids | 1465 aa |
| Exons | 21 |
| GeneCards | ATP7B |
| Human Protein Atlas | ATP7B |
| Neuroprotection | Prevents copper-induced oxidative damage |
| Enzyme cofactor | Supplies copper for copper-dependent enzymes |
| Synaptic modulation | Regulates copper in synaptic vesicles |
| Neurotransmitter synthesis | Supports dopamine β-hydroxylase |
| Associated Diseases | Aging, Als, Alzheimer, Amyotrophic Lateral Sclerosis, Ataxia, Cirrhosis |
| Interactions | CP |
| KG Connections | 23 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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