| Gene Symbol | CACNA1F |
| Full Name | Calcium Voltage-Gated Channel Auxiliary Subunit Alpha1F |
| Aliases | Page for CACNA1F Protein |
| Chromosome | Xp11.23 |
| Function | is located on chromosome Xp11.23 and encodes the alpha1F subunit of voltage-gated calcium channels, known as Cav1.4 |
| Primary Expression | retinal photoreceptors (both rods and cones) where it mediates the influx of calcium ions necessary for synaptic vesicle release and proper transmissi |
| Amino Acids | 166 aa |
| UniProt ID | [O43497](https://www.uniprot.org/uniprot/O43497) |
| Ensembl ID | ENSG00000102040 |
| GeneCards | CACNA1F |
| Human Protein Atlas | CACNA1F |
| Calcium influx | Permits selective Ca²⁺ entry upon membrane depolarization |
| Excitation-contraction coupling | Initiates muscle contraction through calcium-induced calcium release |
| Excitation-transcription coupling | Activates calcium-dependent gene expression |
| Neurotransmitter release | Triggers synaptic vesicle fusion at presynaptic terminals |
| Associated Diseases | neurodegeneration research |
| Interactions | CACNA1A, CACNA1C, CACNA1D, CACNA1E, CACNA1G, CACNA1H |
| KG Connections | 32 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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