| Gene Symbol | CASP6PROTEIN |
| Protein Family | Caspase family (C14 clan, executioner caspase) |
| Protein Type | Protease |
| Function | is an executioner cysteine-aspartate protease encoded by the CASP6 gene. |
| Subcellular Localization | Alzheimer's disease tangles, and cleaves [huntingtin](/proteins/huntingtin-prote |
| Molecular Weight | 34 kDa |
| Amino Acids | 293 aa |
| GeneCards | CASP6PROTEIN |
| Human Protein Atlas | CASP6PROTEIN |
| Gene [@bhatt2012]
CASP6 [@bhatt2020]
UniProt | P55212 |
| PDB | 3OD5, 4FXO |
| Mol. Weight | ~34 kDa (proenzyme), p18+p11 (active) |
| Associated Diseases | Aging, Alzheimer, Alzheimer Disease, Dementia, Huntington Disease, Pyroptosis |
| Interactions | DES, RIPK1, FADD, CEBPB, MCL1, MDM2 |
| KG Connections | 60 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |