| Gene Symbol | CUL3PROTEIN |
| Full Name | Cullin-3 |
| Protein Family | Cullin family (CUL1-7, PARC) |
| Function | The most neuroscience-relevant CRL3 complex is CRL3^KEAP1, which constitutively ubiquitinates NRF2, the master regulator of antioxidant gene expression. |
| Amino Acids | 768 aa |
| UniProt ID | Q13618 |
| GeneCards | CUL3PROTEIN |
| Human Protein Atlas | CUL3PROTEIN |
| 4-helix bundle (4HB, residues 385-455) | Connecting region between N- and C-terminal domains |
| Associated Diseases | ALS |
| Interactions | AKT, APOPTOSIS, AUTOPHAGY, BACH1, BCL2, BECN1 |
| KG Connections | 179 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!