| Gene Symbol | CUL3PROTEIN |
| Full Name | Cullin-3 |
| Protein Family | Cullin family (CUL1-7, PARC) |
| Function | The most neuroscience-relevant CRL3 complex is CRL3^KEAP1, which constitutively ubiquitinates NRF2, the master regulator of antioxidant gene expression. |
| Subcellular Localization | Cytoplasm, Nucleus |
| Amino Acids | 768 aa |
| UniProt ID | Q13618 |
| GeneCards | CUL3PROTEIN |
| Human Protein Atlas | CUL3PROTEIN |
| Protein Name | Cullin-3 |
| Gene | CUL3 |
| PDB | 4AP2 |
| Mass | 88.9 kDa (768 amino acids) |
| Associated Diseases | ALS |
| Interactions | DEPDC5, NPRL3, BACH1, NPRL2, BECN1, NRF2 |
| KG Connections | 182 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |