| Gene Symbol | DGAT1 |
| Full Name | Diacylglycerol O-Acyltransferase 1 |
| Aliases | DGAT1PROTEIN |
| Chromosome | 8q24.3 |
| Protein Type | Enzyme |
| Target Class | Enzyme |
| Function | Small molecule inhibitor of triglyceride synthesis enzyme |
| Mechanism of Action | Small molecule inhibitor of triglyceride synthesis enzyme |
| Primary Expression | multiple cell types within the CNS: |
| Druggability | Low (0.41) |
| Clinical Stage | Phase III |
| Molecular Weight | 53 kDa |
| Amino Acids | 460 aa |
| Exons | 17 |
| Pathways | Astrocyte reactivity signaling |
| UniProt ID | Q3KQR6 |
| Ensembl ID | ENSG00000185088 |
| OMIM | 604035 |
| GeneCards | DGAT1 |
| Human Protein Atlas | DGAT1 |
| Associated Diseases | STROKE, glioblastoma, neurodegeneration |
| Known Drugs/Compounds | Pradigastat |
| Interactions | SOAT1, APOA1, CD36, PLIN2, NR1H3, GBM |
| SciDEX Target | View Target Profile (2 clinical trials) |
| KG Connections | 175 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |