protein 758 words KG: DR3 2026-03-13
kind:proteinsection:proteinsstate:published
Contents

D3 Dopamine Receptor Protein

🔬 Protein Info
Gene SymbolDRD3
AliasesDopamine Receptor D3
Protein TypeReceptor
FunctionThe DR3 gene encodes a G protein-coupled receptor that The D3 dopamine receptor is a D2-like receptor that plays crucial roles in motor control, reward processing, and cognitive functions.
Subcellular Localization</th><td>Plasma membrane, postsynaptic density</td></tr>
PathwaysNF-kB signaling, Nf-Κb, Oxidative Stress, oxidative stress response
Ensembl IDENSG00000151577
GeneCardsDRD3
Human Protein AtlasDRD3
Associated DiseasesAls, Hepatitis, Inflammation, Lupus
InteractionsTAU, NF-ΚB, INFLAMMATION, NEUROINFLAMMATION, AND, AGING
KG Connections33 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36

Related Analyses (10)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (5)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: activates
EGF Gene
gene · KG edge: associated_with
Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: activates

Knowledge Graph (12 edges)

DR3 associated_with EGF
DR3 activates TAU
DR3 activates neuroinflammation
DR3 associated_with AND
DR3 associated_with Lupus
DR3 associated_with Als
DR3 associated_with Hepatitis
DR3 associated_with Inflammation
DR3 activates NF-ΚB
DR3 activates INFLAMMATION