protein 909 words KG: FERROPORTIN 2026-03-19
kind:proteinsection:proteinsstate:published
Contents

Ferroportin (SLC40A1)

🔬 Protein Info
Gene SymbolFERROPORTIN
Chromosome2q32.2
FunctionFerroportin serves as the cellular iron export channel
Subcellular LocalizationPlasma membrane, Endosomes
Molecular Weight70 kDa
Amino Acids571 aa
PathwaysAlpha-Synuclein, Ferroptosis
UniProt ID[Q9NP59](https://www.uniprot.org/uniprot/Q9NP59)
GeneCardsFERROPORTIN
Human Protein AtlasFERROPORTIN
Associated Diseasesneurodegeneration
InteractionsDJ-1, AND, HEPCIDIN, TRANSFERRIN
KG Connections80 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

Blood-Brain Barrier SPM Shuttle System
Score: 0.55
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.53
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Ferroptosis Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
Metal Ion Homeostasis Dysregulation in Alzheimer's Disease
validation · proposed · Score: 0.40

See Also (5)

Packard Center for ALS Research
institution · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: regulates
APOE contributes to Alzheimer's disease by regulating b
hypothesis · KG edge: regulates
DMT1 Gene
gene · KG edge: associated_with
DNA Damage Repair Deficiency Validation Study in Parkin
experiment · KG edge: regulates

Knowledge Graph (12 edges)

FERROPORTIN associated_with TFR1
FERROPORTIN involved_in IRON METABOLISM
FERROPORTIN transports TFR1
FERROPORTIN transports DMT1
FERROPORTIN regulates JUN
FERROPORTIN regulates TFR1
FERROPORTIN associated_with DMT1
FERROPORTIN regulates MAP2
FERROPORTIN regulates Ferritin
FERROPORTIN transports Transferrin