protein 656 words KG: GABRG2PROTEIN 2026-03-13
kind:proteinsection:proteinsstate:published
Contents

GABRG2 Protein — GABA-A Receptor Gamma2 Subunit

🔬 Protein Info
Gene SymbolGABRG2
Full NameGABA-A Receptor Gamma2 Subunit
AliasesGABRG2PROTEIN
Chromosome5
Protein TypeChannel
FunctionThe GABA-A receptor is a ligand-gated chloride channel that mediates fast inhibitory neurotransmission in the central nervous system.
UniProt ID[P18507](https://www.uniprot.org/uniprotkb/P18507/entry)
Ensembl IDENSG00000102265
GeneCardsGABRG2
Human Protein AtlasGABRG2
Associated DiseasesALS, Aging, BLINDNESS, EPILEPSY
InteractionsRb, KCNH2, App, GABRA1, GABRA5
KG Connections41 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (6)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.47
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (9)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (6)

Phenobarbital treatment efficacy study
clinical · proposed · Score: 0.90
Gabra1+/-/Gabrg2+/- mouse model characterization
validation · proposed · Score: 0.90
Optic nerve myelination analysis
exploratory · proposed · Score: 0.88
GABAA receptor subunit expression analysis
exploratory · proposed · Score: 0.85
Clinical characterization of GABRA1/GABRG2 microdeletion pat
clinical · proposed · Score: 0.95

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in