protein 2,567 words KG: GNASPROTEIN
Contents

GNASPROTEIN Protein

🔬 Protein Info
Gene SymbolGNAS
Protein FamilyGαs/olf family of heterotrimeric G proteins
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionendocrine tissues, heart, kidney
Subcellular LocalizationPlasma membrane, cytoplasm, lipid rafts
Molecular Weight45.6 kDa (Gαs), 52 kDa (Gαs-L)
PathwaysMAPK pathway
UniProt IDP63092
GeneCardsGNAS
Human Protein AtlasGNAS
Protein NameGαs (GNAS protein)
PDB IDs1AZT, 2H3M, 3HUR, 4G5V
GTPase ClassificationRas superfamily (small GTPases)
Nucleotide BindingGDP/GTP
VariantAmino Acids
Associated Diseasesneurodegeneration
InteractionsGNAI3, MITOPHAGY, BNIP3L, AKT1, AKT, GNB1
KG Connections31 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph