| Gene Symbol | GRID1 |
| Full Name | Glutamate Ionotropic Receptor Delta Type Subunit 1 |
| Aliases | GRID1PROTEIN |
| Protein Type | Receptor |
| Function | GRID1 (Glutamate Receptor Ionotropic Delta 1), also known as GluRδ1, is a member of the ionotropic glutamate receptor family. |
| Primary Expression | Prefrontal Cortex, Cortex, Ventral Tegmental Area, Substantia Nigra |
| Subcellular Localization | </strong></td><td>Postsynaptic membrane, Dendritic spines</td></tr> |
| Pathways | Autophagy |
| Ensembl ID | ENSG00000148677 |
| GeneCards | GRID1 |
| Human Protein Atlas | GRID1 |
| Dimeric Assembly | GluRδ1 forms homomeric or heteromeric assemblies, with dimerization occurring through the ATD. |
| Channel Properties | Unlike AMPA or NMDA receptors, GluRδ1 forms channels with distinct conductance properties. |
| Splice Variants | Alternative splicing generates multiple isoforms with potentially distinct functions. |
| Postsynaptic Receptor | Expressed at postsynaptic densities where it contributes to synaptic transmission. |
| Associated Diseases | neurodegeneration |
| Interactions | GLUD1, LAMP1, PRKCD, CBLN1, BECN1, MAP1LC3B |
| KG Connections | 36 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |