protein

Albumin

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Albumin: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

218Connections

3Hypotheses

0Analyses

50Outgoing

50Incoming

No summary available yet. View on Wiki →

🔬 Protein Info

Gene Symbol	Albumin
Associated Diseases	Als, Alzheimer, Anxiety, Autism, Depression, Epilepsy
Interactions	MITOCHONDRIA, RAB5, RAB11, JUN, NEURON, BDNF
KG Connections	217 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Albumin["Albumin"] -->|"regulates"| Ischemia["Ischemia"]
    style Ischemia fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Albumin["Albumin"] -->|"encodes"| Aging["Aging"]
    style Aging fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Albumin["Albumin"] -->|"encodes"| Neurodegeneration["Neurodegeneration"]
    style Neurodegeneration fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Albumin["Albumin"] -->|"encodes"| Als["Als"]
    style Als fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Albumin["Albumin"] -->|"activates"| Stroke["Stroke"]
    style Stroke fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Albumin["Albumin"] -->|"interacts"| Cancer["Cancer"]
    style Cancer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    Albumin["Albumin"] -.->|"inhibits"| Alzheimer["Alzheimer"]
    style Alzheimer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    PPARG["PPARG"] -->|"regulates"| Albumin["Albumin"]
    style PPARG fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    PPARGC1A["PPARGC1A"] -->|"regulates"| Albumin["Albumin"]
    style PPARGC1A fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    MITOCHONDRIA["MITOCHONDRIA"] -->|"activates"| Albumin["Albumin"]
    style MITOCHONDRIA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    SREBF1["SREBF1"] -->|"regulates"| Albumin["Albumin"]
    style SREBF1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    LAMP1["LAMP1"] -->|"regulates"| Albumin["Albumin"]
    style LAMP1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style Albumin fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (82)

Target	Relation	Type	Str
Glycocalyx Degradation	inhibits	process	0.85
Ischemia	regulates	disease	0.60
Aging	encodes	disease	0.60
Neurodegeneration	encodes	disease	0.60
Als	encodes	disease	0.60
Aging	activates	disease	0.60
Stroke	activates	disease	0.60
Cancer	interacts_with	disease	0.60
Als	interacts_with	disease	0.60
Alzheimer	inhibits	disease	0.60
Anxiety	associated_with	disease	0.60
Depression	associated_with	disease	0.60
Als	associated_with	disease	0.60
Diabetes	protects_against	disease	0.60
Fibrosis	associated_with	disease	0.60
Als	biomarker_for	disease	0.60
Diabetes	biomarker_for	disease	0.60
Epilepsy	therapeutic_target	disease	0.60
Alzheimer	encodes	disease	0.60
Als	therapeutic_target	disease	0.60
Als	expressed_in	disease	0.60
Aging	regulates	disease	0.60
Schizophrenia	regulates	disease	0.60
Autism	regulates	disease	0.60
Neurodegeneration	expressed_in	disease	0.60
Multiple Sclerosis	associated_with	disease	0.60
Schizophrenia	associated_with	disease	0.60
Als	regulates	disease	0.60
Anxiety	regulates	disease	0.60
Depression	activates	disease	0.60
Dementia	regulates	disease	0.60
Neurodegeneration	regulates	disease	0.60
Neuroinflammation	regulates	disease	0.60
Alzheimer	regulates	disease	0.60
Autism	interacts_with	disease	0.60
Neurodegeneration	activates	disease	0.60
Alzheimer	associated_with	disease	0.60
Autism	associated_with	disease	0.60
Epilepsy	associated_with	disease	0.60
Autism	activates	disease	0.60
Schizophrenia	activates	disease	0.60
Alzheimer	expressed_in	disease	0.60
Huntington	expressed_in	disease	0.60
Als	causes	disease	0.60
Parkinson	regulates	disease	0.60
Anxiety	activates	disease	0.60
Alzheimer	activates	disease	0.60
Als	inhibits	disease	0.60
Neuroinflammation	activates	disease	0.60
Aging	biomarker_for	disease	0.60

Incoming (136)

Source	Relation	Type	Str
PPARG	regulates	gene	0.60
PPARGC1A	regulates	gene	0.60
MITOCHONDRIA	activates	gene	0.60
SREBF1	regulates	gene	0.60
LAMP1	regulates	gene	0.60
EIF4EBP1	regulates	gene	0.60
CTSD	regulates	gene	0.60
NADH	regulates	gene	0.60
ACTB	regulates	gene	0.60
RAS	regulates	gene	0.60
CPT1A	regulates	gene	0.60
RAB7A	regulates	gene	0.60
PPARA	regulates	gene	0.60
CAT	regulates	gene	0.60
MTOR	regulates	gene	0.60
MEF2C	encodes	gene	0.60
ELAVL2	encodes	gene	0.60
SNAP29	encodes	gene	0.60
FUS	encodes	gene	0.60
TDP-43	encodes	gene	0.60
STX17	encodes	gene	0.60
RAB5	inhibits	gene	0.60
CLPP	encodes	gene	0.60
BDNF	encodes	gene	0.60
ALS	encodes	gene	0.60
IGF2BP1	encodes	gene	0.60
MAPK	encodes	gene	0.60
RAB11	inhibits	gene	0.60
YTHDF1	encodes	gene	0.60
AUTOPHAGY	encodes	gene	0.60
METTL3	encodes	gene	0.60
JUN	activates	gene	0.60
NEURON	activates	gene	0.60
BDNF	activates	gene	0.60
STROKE	activates	gene	0.60
CYTOKINES	therapeutic_target	gene	0.60
DNA	interacts_with	gene	0.60
AMYLOID	inhibits	gene	0.60
ALZHEIMER	inhibits	gene	0.60
NRG1	associated_with	gene	0.60
DEPRESSION	associated_with	gene	0.60
ANXIETY	associated_with	gene	0.60
RNA	protects_against	gene	0.60
APOPTOSIS	activates	gene	0.60
PER	biomarker_for	gene	0.60
CATALASE	biomarker_for	gene	0.60
MIRNAS	biomarker_for	gene	0.60
MICRORNAS	biomarker_for	gene	0.60
EGFR	associated_with	gene	0.60
MTOR	activates	gene	0.60

Targeting Hypotheses (3)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
Closed-loop tACS targeting EC-II parvalbumin interneurons to	0.660	Alzheimer's disease	Circuit-level neural dynamics in neurode
Parvalbumin Interneuron Vulnerability Links Lactate Transpor	0.569	neurodegeneration	What is the molecular mechanism by which
TYRO3-STAT1 Axis to Preserve Parvalbumin Interneuron Functio	0.499	neuroinflammation	Why do TAM receptors protect against neu

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Albumin

Understanding Entity Pages

Wiki Pages (20)

Progressive Supranuclear Palsy (PSP)

nhp-validation-animal-model

Blood-Brain Barrier Dysfunction in Neurodegeneration

Blood-Brain Barrier Biology and Crossing Strategies

blood-brain-barrier

Copper Dyshomeostasis in Neurodegeneration

Amyloid Cascade Pathway

Nanobody Therapy for Neurodegenerative Diseases

Thyroid Hormone Signaling Pathway in Neurodegeneration

FGF10 — Fibroblast Growth Factor 10

Cerebral Small Vessel Disease

Beta-Amyloid 42/40 Ratio - Biomarker

neurovascular-dysfunction

Hydrogen Peroxide Metabolism Pathway

bbb-transport-mechanisms

Longevity and Rejuvenation Therapies Landscape

Blood-Brain Barrier Breakdown in Neurodegeneration

Corticobasal Degeneration (CBD) Treatment