CBLN1

Understanding Entity Pages

This page aggregates everything SciDEX knows about CBLN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CBLN1 (Cerebellin 1): secreted synaptogenic protein essential for parallel fiber-Purkinje cell synapse formation, motor learning, and cerebellar development. Implicated in cerebellar ataxia, autism spectrum disorder, and schizophrenia.

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graph TD
    CBLN1["<b>CBLN1</b>"]
    Ms{"Ms"}
    CBLN1 -->|"inhibits"| Ms
    BECN1["BECN1"]
    CBLN1 -->|"inhibits"| BECN1
    Autophagy(["Autophagy"])
    CBLN1 -->|"inhibits"| Autophagy
    SQSTM1["SQSTM1"]
    CBLN1 -->|"inhibits"| SQSTM1
    GLUD1["GLUD1"]
    CBLN1 -->|"interacts with"| GLUD1
    MAP1LC3B["MAP1LC3B"]
    CBLN1 -->|"inhibits"| MAP1LC3B
    LAMP1["LAMP1"]
    CBLN1 -->|"inhibits"| LAMP1
    GRID1["GRID1"]
    CBLN1 -->|"inhibits"| GRID1
    PRKCD["PRKCD"]
    CBLN1 -->|"inhibits"| PRKCD
    AND["AND"]
    CBLN1 -->|"inhibits"| AND
    AUTOPHAGY["AUTOPHAGY"]
    CBLN1 -->|"inhibits"| AUTOPHAGY
    neurodegeneration["neurodegeneration"]
    CBLN1 -->|"implicated in"| neurodegeneration
    SQSTM1 -->|"inhibits"| CBLN1
    MAP1LC3B -->|"inhibits"| CBLN1
    GRID1 -->|"inhibits"| CBLN1
    GLUD1 -->|"interacts with"| CBLN1
    LAMP1 -->|"inhibits"| CBLN1
    PRKCD -->|"inhibits"| CBLN1
    style CBLN1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0