| Gene Symbol | GRIN1PROTEIN |
| Chromosome | 9q34.3 |
| Function | Glutamate Receptor Ionotropic NMDA Subunit 1 (GluN1), encoded by the GRIN1 gene, is the obligatory subunit of the N-methyl-D-aspartate (NMDA) receptor, a glutamate-gated ion channel critical for sy... |
| Primary Expression | the central nervous system, particularly in the hippocampus, cerebral cortex, basal ganglia, and thalamus, where it plays fundamental roles in excitat |
| Molecular Weight | 105 kDa |
| Amino Acids | 938 aa |
| GeneCards | GRIN1PROTEIN |
| Human Protein Atlas | GRIN1PROTEIN |
| PSD-95 | PDZ binding |
| SAP-97 | PDZ binding |
| Homer | PDZ binding |
| CaMKII | Phosphorylation |
| PKA | Phosphorylation |
| PKC | Phosphorylation |
| Src-family kinases | Tyrosine phosphorylation |
| Associated Diseases | Huntington's disease, Memory Impairment |
| Known Drugs/Compounds | D-glutamate |
| Interactions | HCRTR1, DRD2, HRH3, HCRTR2, ADRA1B, DRD1 |
| KG Connections | 48 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |