Contents

Neurogranin (RC3)

🔬 Protein Info

Gene Symbol	NEUROGRANIN
Function	Neurogranin is essential for synaptic plasticity through
Subcellular Localization	</th><td>Postsynaptic dendrites, dendritic spines</td></tr>
Pathways	Calcium signaling, Amyloid, Blood-Brain Barrier
GeneCards	NEUROGRANIN
Human Protein Atlas	NEUROGRANIN
N-terminal Region	Contains the RC3/CAPND domain
Central Region	Serine-rich domain with multiple phosphorylation sites
C-terminal Domain	IQ motif for calmodulin binding
Calmodulin-binding Domain (IQ motif)	Sequence IQVTFVF
Phosphorylation Sites	Multiple serine residues (Ser-4, Ser-5, Ser-8, Ser-10)
Target Protein Interaction Sites	Binds to AKAP79/150
Associated Diseases	Als, Alzheimer, Neuroinflammation
Interactions	BDNF
KG Connections	61 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING