protein 896 words KG: NEUROGRANIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

Neurogranin (RC3)

🔬 Protein Info
Gene SymbolNEUROGRANIN
FunctionNeurogranin is essential for synaptic plasticity through
Subcellular Localization</th><td>Postsynaptic dendrites, dendritic spines</td></tr>
PathwaysCalcium signaling, Amyloid, Blood-Brain Barrier
GeneCardsNEUROGRANIN
Human Protein AtlasNEUROGRANIN
Associated DiseasesAls, Alzheimer, Neuroinflammation
InteractionsBDNF
KG Connections63 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (26)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Prefrontal sensory gating circuit restoration via PV interne
Score: 0.59
Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.56
Blood-Brain Barrier SPM Shuttle System
Score: 0.55

Related Analyses (14)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived

Related Experiments (9)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.46
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.46
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.46
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.46
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.46

See Also (6)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: biomarker_for
Packard Center for ALS Research
institution · KG edge: biomarker_for
Alzheimer Indonesia
institution · KG edge: associated_with
GFAP (Redirect)
redirect · KG edge: associated_with
BACE1 (Redirect)
redirect · KG edge: associated_with

Knowledge Graph (12 edges)

NEUROGRANIN biomarker_for TAU
NEUROGRANIN biomarker_for SYNAPTOPHYSIN
NEUROGRANIN biomarker_for NFL
NEUROGRANIN biomarker_for BACE1
NEUROGRANIN biomarker_for TREM2
NEUROGRANIN therapeutic_target SIGMA1
NEUROGRANIN interacts_with BDNF
NEUROGRANIN activates Calcium signaling
NEUROGRANIN biomarker_for NEUROINFLAMMATION
NEUROGRANIN biomarker_for Neuroinflammation