protein 544 words KG: NLRC3PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

NLRC3 Protein

🔬 Protein Info
Gene SymbolNLRC3
Full NameNLR Family CARD Domain Containing 3
Chromosome16p13.3
Protein TypeReceptor
Functionis a member of the NOD-like receptor (NLR) family of proteins.
Primary Expressionvarious tissues, with highest expression in immune cells and epithelial tissues
Subcellular Localization</strong></td><td>Cytoplasm</td></tr>
Molecular Weight85 kDa
Amino Acids755 aa
Exons14
PathwaysNf-Κb
UniProt IDQ7RTV0
NCBI Gene ID81128
Ensembl IDENSG00000167900
OMIM611362
GeneCardsNLRC3
Human Protein AtlasNLRC3
Associated DiseasesMs
InteractionsTNF, NLRP3, STAT3, TLR4, TRAF6, INFLAMMATION
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (5)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Microbial Inflammasome Priming Prevention
Score: 0.58
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Related Experiments (7)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.46
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.46
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.46
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.46
Mixed Pathology Effects on Parkinson's Disease Progression a
clinical · proposed · Score: 0.46

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in