protein 1,296 words KG: NOXAPROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

NOXA Protein

🔬 Protein Info
Gene SymbolNOXA
Full NamePMA-Induced mRNA 1
Chromosome18q21.32.
Functionencodes a pro-apoptotic BH3-only protein of the BCL-2 family that plays a critical role in regulating mitochondrial apoptosis.
Subcellular Localization</span><span class="infobox-value">Mitochondrial outer membrane, Cytoplasm</span></div>
Molecular Weight6.5 kDa
Amino Acids103 aa
Pathwayspathway: **BH3-Only Protein Function**
UniProt IDQ9Y2X9
NCBI Gene ID5366
Ensembl IDENSG00000141682
OMIM604958
GeneCardsNOXA
Human Protein AtlasNOXA
HIF-1alphainduced by hypoxia, activates NOXA during ischemic conditions[@kim2004]
Associated Diseasesneurodegeneration
InteractionsBAX, PITX3, BCL2, MDM2, CDK4, ATF4
KG Connections31 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph