| Gene Symbol | NRF1 |
| Aliases | NRF1PROTEIN |
| Chromosome | 5q31.1 |
| Protein Family | NRF1/GABP family, transcription factors |
| Protein Type | Gene |
| Function | NRF1 is a critical transcription factor that coordinates the expression of genes involved in mitochondrial function and cellular respiration: [@srensen2020] |
| Primary Expression | tissues with high energy demands: |
| Subcellular Localization | Nucleus |
| Pathways | Apoptosis, Autophagy, Chaperone, Cholesterol, Differentiation |
| UniProt ID | Q16656 |
| GeneCards | NRF1 |
| Human Protein Atlas | NRF1 |
| Gene | NRF1 |
| PDB | 1SRY |
| Mol. Weight | 68 kDa |
| Associated Diseases | ALS, Aging, Alzheimer, Breast Cancer, Cancer |
| Known Drugs/Compounds | nicotinamide, rapamycin |
| Interactions | DRP1, OPA1, MFN1, NRF2, PKC, MAF |
| KG Connections | 490 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |