| Gene Symbol | RAB3BPROTEIN |
| Chromosome | 1p31.1 |
| Function | is a neuronal small GTPase that plays a critical role in regulating synaptic vesicle trafficking and neurotransmitter release. |
| Primary Expression | neurons and neuroendocrine cells, where it functions as a molecular switch controlling vesicle dynamics essential for synaptic communication |
| Subcellular Localization | and membrane association specificity. This region shows greater sequence variation between Rab family members compared t |
| GeneCards | RAB3BPROTEIN |
| Human Protein Atlas | RAB3BPROTEIN |
| Effector Protein | Interaction Domain |
| RIM1α/2α | RAB3-binding domain |
| Rabphilin-3A | RAB3-binding domain |
| Munc13-1/2 | RAB3-binding domain |
| Synaptotagmin-1 | Via RIM |
| Munc18-1 | Via syntaxin |
| Granuphilin | RAB3-binding domain |
| Exophilin-8 | RAB3-binding domain |
| Associated Diseases | ALS, Alzheimer, dementia, frontotemporal, neurodegeneration |
| Interactions | GFAP, CHRNA6, CALB2 |
| KG Connections | 56 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |