| Gene Symbol | rab3c |
| Chromosome | 22 |
| Protein Family | Rab GTPase family |
| Function | The RAB3C (RAB3C, Member RAS Oncogene Family) gene encodes a member of the Rab GTPase family, which is part of the Ras superfamily of small GTPases |
| Primary Expression | neuronal and neuroendocrine tissues, where it plays essential roles in regulated secretion, synaptic vesicle trafficking, and neurotransmitter release |
| Subcellular Localization | Synaptic vesicles, secretory granules, plasma membrane |
| Molecular Weight | ~25-30 kDa |
| Exons | Multiple exons spanning approximately 20 kb |
| Pathways | Glycolysis |
| UniProt ID | Q8WV99 |
| Ensembl ID | ENSG00000172985 |
| Protein Name | RAB3C, Member RAS Oncogene Family |
| GTP/GDP Binding | GTP-bound active, GDP-bound inactive |
| Tissue Specificity | Brain (highest), endocrine cells, neuroendocrine cells |
| Associated Diseases | ALS |
| Interactions | Stat3, Il-6, ATP |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |