gene 891 words KG: RAB3B 2026-03-16
kind:genesection:genesstate:published
Contents

RAB3B Gene

🧬 Gene Info
Gene SymbolRAB3B
Chromosome1p31.1
FunctionThe RAB3B gene encodes a 219-amino acid protein that functions as a molecular switch in vesicle trafficking:
Primary Expressionneuronal and neuroendocrine cells, where they control synaptic vesicle dynamics essential for neurotransmission
Amino Acids219 aa
Ensembl IDENSG00000169258
GeneCardsRAB3B
Human Protein AtlasRAB3B
Associated DiseasesALS, Alzheimer, dementia, frontotemporal, neurodegeneration
InteractionsGFAP, CHRNA6, CALB2
KG Connections56 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Packard Center for ALS Research
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: associated_with
Autoimmune Hypothesis in Alzheimer's Disease
hypothesis · KG edge: contributes_to
RAB5A Gene
gene · KG edge: associated_with
RAB4B Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

RAB3B associated_with RAB5A
RAB3B associated_with RAB11B
RAB3B associated_with RAB10
RAB3B associated_with RAB3A
RAB3B associated_with RAB3C
RAB3B associated_with RAB5
RAB3B associated_with RAB27B
RAB3B associated_with RAB4B
RAB3B associated_with Synaptic Vesicle
RAB3B co_expressed_with SLC1A2