gene 661 words KG: RAB3A 2026-03-22
kind:genesection:genesstate:published
Contents

RAB3A — Ras-Related Protein Rab-3A

🧬 Gene Info
Gene SymbolRAB3A
Full NameRas-Related Protein Rab-3A
Functionis a synaptic vesicle-associated small GTPase that plays a central role in regulating neurotransmitter release[@raba2018][@rab2020].
Subcellular Localization</th><td>Synaptic Vesicles, Presynaptic Terminal</td></tr>
Molecular Weight25 kDa
Amino Acids35 aa
PathwaysSynaptic Vesicle Exocytosis
GeneCardsRAB3A
Human Protein AtlasRAB3A
Associated DiseasesALS
InteractionsRAB27B, LRRK2, AXON, PARKINSON, Raf, SYNAPTOPHYSIN
KG Connections44 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (2)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42

Related Analyses (6)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (10)

LRRK2 G2019S Transgenic Mouse Model
model · KG edge: activates
Packard Center for ALS Research
institution · KG edge: associated_with
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: associated_with
RAB27B Gene
gene · KG edge: activates
RAB11B - RAB11B
gene · KG edge: associated_with

Knowledge Graph (12 edges)

RAB3A associated_with RAB3B
RAB3A associated_with RAB10
RAB3A associated_with RAB11B
RAB3A associated_with RAB3C
RAB3A associated_with RAB5A
RAB3A associated_with RAB5
RAB3A activates RAB27B
RAB3A activates LRRK2
RAB3A associated_with RAB4B
RAB3A causes Synaptic Vesicle