gene 1,504 words KG: RAB5 2026-03-27
kind:genesection:genesstate:published
Contents

RAB5A Gene

🧬 Gene Info
Gene SymbolRAB5A
Full NameRAB5A, member RAS oncogene family
AliasesRas-Related Protein Rab-5A
Chromosome3p24.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight~24 kDa
Amino Acids218 aa
PathwaysMAPK signaling
UniProt IDP20339
NCBI Gene ID5868
Ensembl IDENSG00000112984
OMIM171585
GeneCardsRAB5A
Human Protein AtlasRAB5A
Protein Length218 amino acids
Associated DiseasesALS
InteractionsNEURODEGENERATIVE DISEASES
KG Connections32 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (30)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.68
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61

Related Analyses (12)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (5)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: associated_with
ALS2 (Alsin)
gene · KG edge: causes
Amyotrophic Lateral Sclerosis
redirect · KG edge: causes

Knowledge Graph (12 edges)

RAB5 regulates VESICLE_TRAFFICKING
RAB5 regulates vesicle_trafficking
RAB5 inhibits neurodegeneration
RAB5 therapeutic_target SNAP29
RAB5 therapeutic_target IGF2BP1
RAB5 therapeutic_target LONP1
RAB5 therapeutic_target BDNF
RAB5 therapeutic_target FUS
RAB5 associated_with RAB3B
RAB5 associated_with RAB5A