protein 723 words KG: STAU2PROTEIN
Contents

Staufen2 Protein

🔬 Protein Info
Gene SymbolSTAU2PROTEIN
Full NameStaufen2
Protein FamilyStaufen family, RNA-binding proteins
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight~63 kDa (isoform-dependent)
UniProt IDQ9NUR2
GeneCardsSTAU2PROTEIN
Human Protein AtlasSTAU2PROTEIN
N-terminal dsRNA-binding domains (RBDs)4-5 dsRNA-binding domains that bind to target mRNAs
Staufen domainC-terminal domain mediating protein-protein interactions
Microtubule-binding regionMaps to N-terminal region for transport
Multiple isoformsGenerated by alternative splicing (STAU2 isoforms 1-5)
Associated DiseasesAls, Amyotrophic Lateral Sclerosis, Ataxia, Dementia, frontotemporal dementia
Known Drugs/Compoundsrapamycin
InteractionsmTOR, MTOR, RNA, STAU1, STAUFEN2
KG Connections74 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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