| Gene Symbol | TGFBR2 |
| Full Name | Transforming Growth Factor Beta Receptor 2 |
| Aliases | TβR-II, TBR2, TGF-β type II receptor |
| Chromosome | 3p22.1 |
| Protein Family | TGF-β receptor family |
| Function | TGFBR2 (Transforming Growth Factor Beta Receptor 2) encodes the type II TGF-β receptor, a transmembrane serine/threonine kinase that is essential for TGF-β signaling. |
| Primary Expression | the brain: |
| Subcellular Localization | Plasma membrane, early endosomes |
| Molecular Weight | ~70 kDa (567 amino acids) |
| Pathways | TGF-β, TGF-β signaling, PI3K, MAPK |
| UniProt ID | [P37173](https://www.uniprot.org/uniprot/P37173) |
| Ensembl ID | ENSG00000163513 |
| GeneCards | TGFBR2 |
| Human Protein Atlas | TGFBR2 |
| Protein Name | TGFBR2 (TGF-β Receptor 2) |
| Associated Diseases | Als, Cancer, Carcinoma, Colorectal Cancer, Gastric Cancer |
| Interactions | PIEZO1, AND, GENES, SMAD2, TGFBR1, TGF |
| KG Connections | 76 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |