| Gene Symbol | TAB2 |
| Aliases | TAK1-Binding Protein 2 |
| Chromosome | 6p25.1 |
| Protein Family | TAK1-binding proteins |
| Protein Type | Adaptor Protein |
| Function | TAB2 is an adaptor protein that links TAK1 to TRAF6 in the NF-κB activation pathway. |
| Primary Expression | neurons and glial cells, where it regulates inflammatory responses |
| Molecular Weight | 77.8 kDa |
| Amino Acids | 693 aa |
| Pathways | cascade: ### TAK1 Activation Complex, NF-κB, MAPK, MAPK pathway, MAPK signaling |
| UniProt ID | [Q9Y2K2](https://www.uniprot.org/uniprot/Q9Y2K2) |
| GeneCards | TAB2 |
| Human Protein Atlas | TAB2 |
| Associated Diseases | neurodegeneration |
| Interactions | APOPTOSIS, HUNTINGTON, HUNTINGTON'S DISEASE, JNK, MICRORNAS, MIRNAS |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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