gene

MIRNAS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MIRNAS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1731Connections

0Hypotheses

0Analyses

50Outgoing

50Incoming

0Experiments

0Debates

Summary

MIRNAS is a gene implicated in neurodegeneration research. Key relationships include: regulates, therapeutic target, associated with. Associated with ALS, Aging, Als. Connected to 1199 entities in the SciDEX knowledge graph.

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🧬 Gene Info

Gene Symbol	MIRNAS
Primary Expression	Ca1, Hippocampus, Prefrontal Cortex, Cortex, Thalamus
Pathways	Apoptosis, Immune Response, Oxidative Stress, Differentiation, Microrna
GeneCards	MIRNAS
Human Protein Atlas	MIRNAS
Associated Diseases	Aging, Als, Alzheimer, ALZHEIMERS_DISEASE, Amyotrophic Lateral Sclerosis
Interactions	ABCA1, ACSL4, Actin, AGING, AGO2, AKT
KG Connections	1712 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Pathway Diagram

graph TD
    MIRNAS["MIRNAS"] -->|"associated"| Cancer["Cancer"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Als["Als"]
    MIRNAS["MIRNAS"] -.->|"inhibits"| Tumor["Tumor"]
    MIRNAS["MIRNAS"] -->|"regulates"| Alzheimer["Alzheimer"]
    MIRNAS["MIRNAS"] -->|"activates"| Aging["Aging"]
    MIRNAS["MIRNAS"] -->|"activates"| Tumor_1["Tumor"]
    HNRNPA1["HNRNPA1"] -.->|"inhibits"| MIRNAS["MIRNAS"]
    GENES["GENES"] -->|"associated"| MIRNAS["MIRNAS"]
    LOX["LOX"] -->|"regulates"| MIRNAS["MIRNAS"]
    MICRORNAS["MICRORNAS"] -->|"activates"| MIRNAS["MIRNAS"]
    style MIRNAS fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1306)

Target	Relation	Type	Str
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
miRNAs	encodes	protein	0.00
Differentiation	regulates	pathway	1.00
APOPTOSIS	activates	gene	1.00
Aging	regulates	disease	1.00
CANCER	biomarker_for	gene	1.00
INFLAMMATION	regulates	gene	1.00
MICRORNAS	regulates	gene	1.00
OVERVIEW	regulates	gene	1.00
Tumor	therapeutic_target	disease	1.00
CANCER	therapeutic_target	gene	1.00
Cancer	biomarker_for	disease	1.00
EXOSOMES	therapeutic_target	gene	1.00
Cancer	expressed_in	disease	1.00
MICRORNAS	expressed_in	gene	1.00
Als	regulates	disease	1.00
Aging	therapeutic_target	disease	1.00
Mapk	regulates	pathway	1.00
Tumor	activates	disease	1.00
Als	activates	disease	1.00
APOPTOSIS	therapeutic_target	gene	1.00
Cholesterol	regulates	pathway	1.00
AUTOPHAGY	therapeutic_target	gene	1.00
APOPTOSIS	regulates	gene	1.00
Cancer	therapeutic_target	disease	1.00
Inflammation	expressed_in	disease	1.00
AKT	therapeutic_target	gene	1.00
Apoptosis	therapeutic_target	pathway	1.00
GENES	therapeutic_target	gene	1.00
Oxidative Stress	therapeutic_target	pathway	1.00
CANCER	regulates	gene	1.00
Apoptosis	regulates	pathway	1.00
GENES	activates	gene	1.00
Inflammation	therapeutic_target	disease	1.00
Als	inhibits	disease	1.00
Immune Response	regulates	pathway	1.00
PI3K	therapeutic_target	gene	1.00
Tumor	regulates	disease	1.00
Cancer	regulates	disease	1.00
Als	therapeutic_target	disease	1.00
Cancer	activates	disease	1.00
Tumor	inhibits	disease	1.00
GENES	regulates	gene	1.00
Epigenetic	regulates	pathway	1.00
Inflammation	regulates	disease	1.00
OXIDATIVE STRESS	therapeutic_target	gene	1.00
Alzheimer	therapeutic_target	disease	1.00
Apoptosis	activates	pathway	1.00
MICRORNAS	therapeutic_target	gene	1.00
Als	expressed_in	disease	1.00

Incoming (425)

Source	Relation	Type	Str
MIRNAS	encodes	gene	0.00
benchmark_ot_ad_answer_key:MIRNAS	data_in	dataset_row	0.00
h-test-8d254307	targets	hypothesis	1.00
h-test-full-8d254307	targets_gene	hypothesis	0.90
24957213	are involved in	paper	0.90
astrocytic ApoE	produces	protein	0.90
ApoE4	inhibits	protein	0.80
ACUPUNCTURE	regulates	treatment	0.80
BCL2L11	targets	gene	0.80
MICRORNAS	regulates	gene	0.70
ALZHEIMER'S DISEASE	regulates	gene	0.70
TP53	regulates	gene	0.70
INFLAMMATION	regulates	gene	0.70
AKT	regulates	gene	0.60
AKT3	regulates	gene	0.60
MICRORNAS	activates	gene	0.60
OVERVIEW	activates	gene	0.60
SIRT1	therapeutic_target	gene	0.60
RB1CC1	therapeutic_target	gene	0.60
LOX	regulates	gene	0.60
NLRP3	therapeutic_target	gene	0.60
GLUT4	therapeutic_target	gene	0.60
PDGFRA	activates	gene	0.60
SMAD3	therapeutic_target	gene	0.60
GENES	regulates	gene	0.60
GENES	activates	gene	0.60
VEGF	activates	gene	0.60
TRAF6	biomarker_for	gene	0.60
P38	biomarker_for	gene	0.60
CD4	biomarker_for	gene	0.60
BACE1	therapeutic_target	gene	0.60
OVERVIEW	therapeutic_target	gene	0.60
PTEN	therapeutic_target	gene	0.60
RB1	therapeutic_target	gene	0.60
MICRORNAS	therapeutic_target	gene	0.60
CTSD	biomarker_for	gene	0.60
AKT	therapeutic_target	gene	0.60
FLNA	biomarker_for	gene	0.60
STXBP2	biomarker_for	gene	0.60
SOX9	therapeutic_target	gene	0.60
RANK	therapeutic_target	gene	0.60
ALOX15	activates	gene	0.60
HNRNPA1	activates	gene	0.60
LOX	activates	gene	0.60
TP53	expressed_in	gene	0.60
MTOR	interacts_with	gene	0.60
PI3K	therapeutic_target	gene	0.60
THBS2	associated_with	gene	0.60
NFKBIA	biomarker_for	gene	0.60
GENES	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MIRNAS in their description or question text

No additional research found