| Gene Symbol | TIM23 |
| Aliases | TIM23 complex |
| Function | Given the central role of mitochondria in neuronal function—particularly in high-energy demanding dopaminergic neurons and other neuronal subtypes—TIM23-mediated protein import is fundamental to ne... |
| Subcellular Localization | inner mitochondrial membrane |
| Molecular Weight | 16 kDa |
| Pathways | mitophagy |
| GeneCards | TIM23 |
| Human Protein Atlas | TIM23 |
| Component | Function |
| TIM23 | Channel-forming subunit, lateral gate |
| Tim17 | IMS domain, substrate access |
| Tim21 | Assembly, interaction with OXPHOS |
| Tim50 | Transfer to Tim23 from TOM |
| Tim44 (matrix) | Motor recruitment |
| Associated Diseases | Parkinson's disease, Alzheimer's disease |
| Interactions | OPTINEURIN, HSP60, PINK1, NDP52 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |