🧫

SPP1-mediated microglial synaptic engulfment assay

active
experiment Created: 2026-04-06T12:26:59 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-01066b75-ea4d-4a55-8465-7
🧫 Experiment Protocol Cell Biologyproposed
Related Entities
SPP1
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:26:59.139797'}
p_valueNone
protocolPhagocytosis assays measuring synaptic engulfment and expression of C1qa, Grn, Ctsb markers
effect_sizeNone
sample_sizeNone
source_pmid36747024
extracted_at2026-04-06T05:26:59.117766
_schema_version1
experiment_typecell_biology
success_criteriaSignificant upregulation of phagocytic markers and increased synaptic engulfment with SPP1
expected_outcomesSPP1-dependent increase in microglial synaptic engulfment and phagocytic markers
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
28
Outgoing
23
0 supporting 0 contradicting 0 neutral
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