🧫
Spp1 knockout prevents synaptic loss in AD mouse models
active
experiment
Created: 2026-04-06T12:26:59
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-65ec258c-9969-4522-841b-2
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:26:59.156666'} |
| p_value | None |
| protocol | Genetic knockout of Spp1 in AD mouse models with assessment of synaptic density and integrity |
| effect_size | None |
| sample_size | None |
| source_pmid | 36747024 |
| extracted_at | 2026-04-06T05:26:59.117768 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Preserved synaptic density in Spp1 knockout compared to controls |
| expected_outcomes | Prevention of synaptic loss in Spp1 knockout mice |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
27
Outgoing
22
0 supporting
0 contradicting
0 neutral
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