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SPP1 Gene

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-spp1
Related Entities
SPP1
Metadata
sluggenes-spp1
entity_typegene
kg_node_idSPP1
🌍 Provenance Graph 1 nodes, 0 edges

No provenance edges found

Linked Artifacts (83)
mentions🧫Single-cell RNA sequencing of microglial states in AD hippoc80%
related🧫Single-cell RNA sequencing of microglial states in AD hippoc72%
mentions🧫SPP1-mediated microglial synaptic engulfment assay70%
mentions🧫SPP1 upregulation in perivascular cells in AD mouse models70%
mentions🧫Spp1 knockout prevents synaptic loss in AD mouse models70%
mentions🧫Cell-cell interaction analysis of perivascular-microglial cr70%
related🧫SPP1-mediated microglial synaptic engulfment assay63%
related🧫SPP1 upregulation in perivascular cells in AD mouse models63%
related🧫Spp1 knockout prevents synaptic loss in AD mouse models63%
related🧫Cell-cell interaction analysis of perivascular-microglial cr63%
see_also📖Astrocytes60%
see_also📖Apoptosis in Neurodegeneration60%
see_also📖Amyloid-Related Imaging Abnormalities (ARIA)60%
see_also📖ANXA2 — Annexin A260%
see_also📖ATF3 Gene60%
see_also📖BLM — Bloom Syndrome Protein60%
see_also📖C1QA Gene60%
see_also📖TIMP1 Gene60%
see_also📖Alzheimer Indonesia60%
see_also📖Apoptosis Pathway in Neurodegeneration60%
see_also📖blarcamesine-axon60%
see_also📖ATM Gene60%
see_also📖CAMK4 — Calcium/Calmodulin-Dependent Kinase 460%
see_also📖KIF20A — Kinesin Family Member 20A60%
see_also📖NME1 - NME Nucleoside Diphosphate Kinase 160%
see_also📖hypotheses-apoe-contributes-alzheimers-disease-regulat60%
see_also📖syna60%
see_also📖RPS18 — Ribosomal Protein S1860%
see_also📖SLC9A1 — Sodium/Hydrogen Exchanger 160%
see_also📖TAC1 Gene60%
see_also📖Accelerating Medicines Partnership for Alzheimer's Dise60%
see_also📖Dementia Australia60%
see_also📖Autophagy Enhancement Drug Screening for Neurodegeneration60%
mentions🧪Complement C1q Mimetic Decoy Therapy50%
mentions🧪Complement C1q Subtype Switching50%
mentions🧪Complement-Mediated Synaptic Pruning Dysregulation50%
mentions🧪Glial Glycocalyx Remodeling Therapy50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Complement C1QA Spatial Gradient in Cortical Layers50%
mentions🧪Optogenetic Microglial Deactivation via Engineered Inhibitor50%
mentions🧪Fractalkine Axis Amplification via CX3CR1 Positive Allosteri50%
mentions🧪Stress Granule Phase Separation Modulators50%
mentions🧪Phase-Separated Organelle Targeting50%
mentions🧪RNA Granule Nucleation Site Modulation50%
mentions🧪HSP90-Tau Disaggregation Complex Enhancement50%
mentions🧪Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪CYP46A1 Overexpression Gene Therapy50%
mentions🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th50%
related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬What are the mechanisms underlying 4r-tau strain-specific sp50%
related🔬What are the mechanisms underlying neuroinflammation resolut50%
related🔬Investigate how lipid raft composition (cholesterol metaboli50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬What gene expression changes in the aging mouse brain predic50%
related🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas50%
related🧪GFAP-Positive Reactive Astrocyte Subtype Delineation50%
related🧪Microbial Inflammasome Priming Prevention50%
related🧪Piezoelectric Nanochannel BBB Disruption50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬What are the mechanisms underlying perivascular spaces and g50%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Complement C1q Mimetic Decoy Therapy40%
related🧪CYP46A1 Overexpression Gene Therapy40%
related🧪Complement C1q Subtype Switching40%
related🧪Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th40%
related🧪Glial Glycocalyx Remodeling Therapy40%
mentions🔬What are the mechanisms underlying 4r-tau strain-specific sp35%
mentions🔬What are the mechanisms underlying synaptic pruning by micro35%
mentions🔬What gene expression changes in the aging mouse brain predic35%
mentions🔬SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas35%
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