🧫
TRIM21-mediated K63-linked ubiquitination of G3BP1
active
experiment
Created: 2026-04-04T05:25:10
By: experiment_extractor
Quality:
95%
✓ SciDEX
ID: experiment-exp-0732dce4-a7d4-4253-abdc-f
🧫 Experiment Protocol
Protein Interactionproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-04T05:25:10.857049'} |
| p_value | None |
| protocol | co-immunoprecipitation, ubiquitination assays, in vitro LLPS assays, protein interaction studies |
| effect_size | None |
| sample_size | None |
| source_pmid | 36692217 |
| extracted_at | 2026-04-04T05:25:03.816839 |
| _schema_version | 1 |
| experiment_type | protein_interaction |
| success_criteria | detection of K63-linked ubiquitin modification on G3BP1 and inhibition of LLPS |
| expected_outcomes | TRIM21 directly ubiquitinates G3BP1 and inhibits phase separation |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
82
Outgoing
15
0 supporting
0 contradicting
0 neutral
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