🧫
Epigenetic Regulation Dysfunction in Alzheimer's and Parkinson's Disease
experiment
Created: 2026-04-02T17:01:41
By: crosslink-v2
Quality:
67%
✓ SciDEX
ID: experiment-exp-wiki-experiments-epigenet
🧫 Experiment Protocol
Clinical
Metadata
| experiment_type | clinical |
| source | {'type': 'manual', 'source_name': 'wiki', 'extraction_date': '2026-04-16T01:00:16.901261Z', 'extracted_by': 'backfill_v1'} |
| entities | {'genes': ['BRD4/HDAC/HDAC3'], 'diseases': ["Alzheimer's Disease"]} |
| model_system | human |
| summary | # Epigenetic Regulation Dysfunction in Alzheimer's and Parkinson's Disease ## Background and Rationale Neurodegenerative diseases like Alzheimer's (AD) and Parkinson's disease (PD) exhibit complex pat |
| replication_status | single_study |
| methodology_notes | Phase 1: Sample Collection and Processing (Months 1-6): Collect post-mortem brain tissue from frontal cortex, hippocampus, and substantia nigra regions from AD (n=60), PD (n=60), and control (n=40) su |
| primary_outcome | Validate Epigenetic Regulation Dysfunction in Alzheimer's and Parkinson's Disease |
| extraction_metadata | {'extraction_confidence': 0.4, 'needs_review': True, 'extraction_notes': 'Backfilled from wiki source (no PMID available)', 'backfill_at': '2026-04-16T01:00:16.901267'} |
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