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Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice.
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📄 Paper Details
Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice.
Low BE, Christianson GJ, Lowell E, Qin W, Wiles MV
Abstract
1. MAbs. 2020 Jan-Dec;12(1):1829334. doi: 10.1080/19420862.2020.1829334. Functional humanization of immunoglobulin heavy constant gamma 1 Fc domain human FCGRT transgenic mice. Low BE(1), Christianson GJ(1), Lowell E(2), Qin W(2), Wiles MV(1). Author information: (1)The Jackson Laboratory , Bar Harbor, ME, USA. (2)Previously at the Jackson Laboratory , Bar Harbor, ME, USA. A major asset of many monoclonal antibody (mAb)-based biologics is their persistence in circulation. The MHC class I f...
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📊 Evidence Profile
Evidence Balance
+0%
Certainty
15%
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Outgoing
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