Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about 116B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| Ischemic Stroke | treats | disease | 0.95 |
| Infarct Volume | downregulates | biomarker | 0.92 |
| blood-brain barrier | associated_with | brain_region | 0.92 |
| microglia activation | suppresses | process | 0.90 |
| astrocyte activation | suppresses | process | 0.90 |
| inflammation | suppresses | process | 0.90 |
| Oxidative Stress | associated_with | process | 0.90 |
| Mitochondrial Function | associated_with | process | 0.90 |
| Blood-Brain Barrier | associated_with | process | 0.90 |
| ROS | associated_with | process | 0.88 |
| Microglia | inhibits | cell_type | 0.88 |
| Astrocytes | inhibits | cell_type | 0.88 |
| microtubule dynamics | modulates | process | 0.85 |
| microglia activation | inhibits | process | 0.85 |
| astrocyte activation | inhibits | process | 0.85 |
| CAT | upregulates | protein | 0.85 |
| GPX4 | upregulates | protein | 0.85 |
| Gpx4 | upregulates | enzyme | 0.85 |
| mitochondrial function | associated_with | process | 0.85 |
| MAPK | inhibits | protein | 0.82 |
| SOD1 | upregulates | gene | 0.78 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||