aggf1

Understanding Entity Pages

This page aggregates everything SciDEX knows about aggf1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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flowchart TD
    N0["AGGF1"]
    N1["VEGFA"]
    N0 -->|"activates"| N1
    N2["FLT4"]
    N0 -->|"upregulates"| N2
    N3["EPHB4"]
    N0 -->|"upregulates"| N3
    N4["DAB2"]
    N0 -->|"upregulates"| N4
    N5["AKT"]
    N0 -->|"activates"| N5
    N6["TNFSF12"]
    N0 -->|"upregulates"| N6
    N7["ITGA7"]
    N0 -->|"binds"| N7
    N8["TP53"]
    N0 -->|"stabilizes"| N8
    N9["GATA1"]
    N9 -->|"upregulates"| N0
    N10["HIF1A"]
    N10 -->|"upregulates"| N0
    N11["PERK"]
    N0 -.->|"inhibits"| N11
    N12["MCL1"]
    N0 -->|"upregulates"| N12
    N13["neurodegeneration"]
    N0 -->|"implicated in"| N13

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 gene
    class N2 gene
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N11 gene
    class N12 gene