concept

AGTR1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AGTR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections
0Hypotheses
0Analyses
10Outgoing
6Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameAGTR1
Key Genes/ProteinsMARK4, MICRORNAS, APOPTOSIS, AND, GENES
Related PathwaysApoptosis, Angiogenesis

Wiki Pages (5)

Knowledge base pages for this entity

substantia-nigra

brain_region · 4437 words

Dopaminergic Neurons

cell · 2519 words

dopaminergic-neurons

general · 1947 words

Subfornical Organ Neurons

cell · 869 words

Organum Vasculosum of the Lamina Terminalis Neurons

cell · 796 words

Pathway Diagram

graph TD
    AGTR1["AGTR1"]
    AGTR1 -->|"mediates"| Oxidative_Damage["Oxidative Damage"]
    AGTR1 -->|"activates"| MARK4["MARK4"]
    AGTR1 -->|"target for"| MICRORNAS["MICRORNAS"]
    AGTR1 -->|"target for"| Apoptosis["Apoptosis"]
    AGTR1 -->|"activates"| Angiogenesis["Angiogenesis"]
    AGTR1 -->|"target for"| APOPTOSIS["APOPTOSIS"]
    miR_199a_5p["miR-199a-5p"] -->|"targets"| AGTR1
    APOPTOSIS -->|"target for"| AGTR1
    GENES["GENES"] -->|"activates"| AGTR1
    AND["AND"] -->|"activates"| AGTR1
    MARK4 -->|"activates"| AGTR1

Outgoing (10)

TargetRelationTypeStr
Oxidative Damagemediatesprocess0.90
MARK4activatesgene0.60
MICRORNAStherapeutic_targetgene0.60
Apoptosistherapeutic_targetpathway0.60
MICRORNASactivatesgene0.60

Incoming (6)

SourceRelationTypeStr
miR-199a-5ptargetsbiomarker0.95
APOPTOSIStherapeutic_targetgene0.60
GENESactivatesgene0.60
ANDactivatesgene0.60
APOPTOSISactivatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found