Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AGTR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | AGTR1 |
| Key Genes/Proteins | MARK4, MICRORNAS, APOPTOSIS, AND, GENES |
| Related Pathways | Apoptosis, Angiogenesis |
Knowledge base pages for this entity
graph TD
AGTR1["AGTR1"]
AGTR1 -->|"mediates"| Oxidative_Damage["Oxidative Damage"]
AGTR1 -->|"activates"| MARK4["MARK4"]
AGTR1 -->|"target for"| MICRORNAS["MICRORNAS"]
AGTR1 -->|"target for"| Apoptosis["Apoptosis"]
AGTR1 -->|"activates"| Angiogenesis["Angiogenesis"]
AGTR1 -->|"target for"| APOPTOSIS["APOPTOSIS"]
miR_199a_5p["miR-199a-5p"] -->|"targets"| AGTR1
APOPTOSIS -->|"target for"| AGTR1
GENES["GENES"] -->|"activates"| AGTR1
AND["AND"] -->|"activates"| AGTR1
MARK4 -->|"activates"| AGTR1| Target | Relation | Type | Str |
|---|---|---|---|
| Oxidative Damage | mediates | process | 0.90 |
| MARK4 | activates | gene | 0.60 |
| MICRORNAS | therapeutic_target | gene | 0.60 |
| Apoptosis | therapeutic_target | pathway | 0.60 |
| MICRORNAS | activates | gene | 0.60 |
| Angiogenesis | activates | pathway | 0.60 |
| Apoptosis | activates | pathway | 0.60 |
| APOPTOSIS | therapeutic_target | gene | 0.60 |
| AND | activates | gene | 0.60 |
| GENES | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||