Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BAI1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | BAI1 |
| Chromosome | 8q24.12 |
| Protein Type | Receptor |
| Function | is a member of the adhesion G protein-coupled receptor (GPCR) family and contains multiple functional domains that mediate its interactions with various cellular partners. |
| Molecular Weight | 175 kDa |
| Amino Acids | 584 aa |
| Exons | 31 |
| Pathways | Complement |
| Ensembl ID | ENSG00000181789 |
| GeneCards | BAI1 |
| Human Protein Atlas | BAI1 |
| BAI1-A | Full-length isoform with all functional domains |
| BAI1-B | Truncated variant lacking part of extracellular domain |
| BAI1-V1 | Brain-specific alternative splice isoform |
| BAI1-V2 | Endothelial cell-enriched isoform |
| Associated Diseases | neurodegeneration |
| Interactions | RTN4, EGF, AND, SYNAPSE |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
BAI1["<b>BAI1</b>"]
Ms{"Ms"}
BAI1 -->|"interacts with"| Ms
RTN4["RTN4"]
BAI1 -->|"interacts with"| RTN4
Complement(["Complement"])
BAI1 -->|"regulates"| Complement
neurodegeneration["neurodegeneration"]
BAI1 -->|"implicated in"| neurodegeneration
CD44["CD44"]
CD44 -->|"associated with"| BAI1
COMPLEMENT["COMPLEMENT"]
COMPLEMENT -->|"regulates"| BAI1
C1Q["C1Q"]
C1Q -->|"associated with"| BAI1
MET["MET"]
MET -->|"associated with"| BAI1
ADCY5["ADCY5"]
ADCY5 -->|"associated with"| BAI1
style BAI1 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||