Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about C1QAPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
C1Qa Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
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| Gene Symbol | C1QAPROTEIN |
| Full Name | C1qA |
| Protein Type | Protein |
| Target Class | Signaling Protein |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Mechanism of Action | Complement cascade inhibitor or antibody-mediated neutralization |
| Druggability | Low (0.41) |
| Clinical Stage | Phase II |
| UniProt ID | Search UniProt |
| GeneCards | C1QAPROTEIN |
| Human Protein Atlas | C1QAPROTEIN |
| Associated Diseases | AD, Aging, ALI, Als, Alzheimer |
| Known Drugs/Compounds | ANX005 |
| Interactions | AIF1, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND, ANXIETY |
| SciDEX Target | View Target Profile (7 clinical trials) |
| SciDEX Hypotheses | Complement C1q Mimetic Decoy Therapy Complement C1QA Spatial Gradient in Cortical Layer Complement C1q Subtype Switching (+3 more) |
| KG Connections | 711 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
C1QAPROTEIN["C1QAPROTEIN"]
neurodegeneration["neurodegeneration"]
C1QAPROTEIN -->|"implicated_in"| neurodegeneration
style C1QAPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity