Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CALCNN1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | CALM1 |
| Full Name | Calmodulin 1 |
| Chromosome | 14q32.11 |
| Protein Family | Calmodulin family |
| Function | Binds 4 Ca2+ ions upon calcium elevation |
| Primary Expression | all cell types - High in brain: Particularly in cortex, hippocampus, cerebellum - Isoform |
| Molecular Weight | 16.7 kDa |
| Amino Acids | 149 aa |
| Pathways | mTOR, mtor |
| UniProt ID | P62158 |
| NCBI Gene ID | 801 |
| Ensembl ID | ENSG00000198668 |
| GeneCards | CALM1 |
| Human Protein Atlas | CALM1 |
| Chromosomal location | 14q32.11 |
| Associated Diseases | Aging, Als, Alzheimer, Ms |
| Interactions | AKT1, ALZHEIMER, ASPM, AURKB, CDC42, EGFR |
| KG Connections | 122 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
CALCNN1["CALCNN1"]
neurodegeneration["neurodegeneration"]
CALCNN1 -->|"implicated_in"| neurodegeneration
style CALCNN1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CALCNN1 in their description or question text
No additional research found