Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Celastrol: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| CASP3 | activates | gene | 0.95 |
| GSDME | activates | gene | 0.95 |
| Reactive Oxygen Species | promotes | process | 0.95 |
| Pyroptosis | associated_with | process | 0.95 |
| Atp Secretion | associated_with | biomarker | 0.85 |
| Ldh Release | associated_with | biomarker | 0.85 |
| CALR | upregulates | gene | 0.85 |
| Cancer | treats | disease | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Zwitterionic Nanogels | transports | compound | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||