concept

CIRCFRMD4A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CIRCFRMD4A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

11Outgoing

5Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	CIRCFRMD4A

Wiki Pages (1)

Knowledge base pages for this entity

EWSR1 Gene

gene · 657 words

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Pathway Diagram

graph TD
    CIRCFRMD4A["CIRCFRMD4A"]
    CIRCFRMD4A -->|"suppresses"| Cancer["Cancer"]
    CIRCFRMD4A -->|"promotes"| Cuproptosis["Cuproptosis"]
    CIRCFRMD4A -->|"interacts"| PKM2["PKM2"]
    CIRCFRMD4A -->|"modulates"| Glycolytic_Metabolism["Glycolytic Metabolism"]
    CIRCFRMD4A -->|"mediates"| Glycolytic_Reprogramming["Glycolytic Reprogramming"]
    CIRCFRMD4A -->|"inhibits"| Cancer_Development["Cancer Development"]
    p53["p53"] -->|"activates"| CIRCFRMD4A
    TP53["TP53"] -->|"upregulates"| CIRCFRMD4A
    FRMD4A["FRMD4A"] -->|"expressed in"| CIRCFRMD4A
    EWSR1["EWSR1"] -->|"promotes"| CIRCFRMD4A

Outgoing (11)

Target	Relation	Type	Str
Cuproptosis	promotes	process	0.95
Glycolytic Metabolism	modulates	pathway	0.95
Cancer	suppresses	disease	0.95
PKM2	interacts_with	protein	0.95
PKM2	inhibits	protein	0.95
Cuproptosis	involved_in	process	0.94
Glycolytic Reprogramming	mediates	process	0.93
Cancer Development	inhibits	disease	0.92
PKM2	inhibits	protein	0.92
Elesclomol	associated_with	drug	0.90
PKM2	interacts_with	protein	0.90

Incoming (5)

Source	Relation	Type	Str
p53	activates	protein	0.95
TP53	upregulates	gene	0.95
EWSR1	promotes	gene	0.90
FRMD4A	expressed_in	gene	0.90
EWSR1	associated_with	protein	0.88

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found